Tag: Novel

A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models

The Hippo pathway regulates the YAP and TAZ transcriptional coactivators, which are often upregulated in human cancers. YAP/TAZ partner with TEAD transcription factors to drive cancer phenotypes. Because mutations in the Hippo pathway genes NF2 and LATS2 lead to YAP/TAZ hyperactivation, mesothelioma...

Synopsis Of THE OMEGA CONSPIRACY Novel

The novel begins with the introduction of Jonathan Margolis to Dr. Carmichael after he throws a fit at a pool on a class field trip and is taken to Columbia Presbyterian Hospital, where he encounters Dr. Eldin Carmichael. Dr. Carmichael discovers through the drawings that Jonathan has brought wit...

How to Become an Indie Game Developer

Visual novels combine text, images, sound, and choices to create an immersive experience. They are popular in Japan and have a loyal fanbase around the world. I always liked visual novels and wanted to make one of my own. Inspired by watching Welcome to the NHK. In this blog post, I'm sh...

How I Used Midjourney To Bring My Graphic Novel to Life

For over a year, I have been gestating a story that has been knocking on my brain to come out into the world. It is a story that speaks of unity, hope, and helping us to recognize the strengths and similarities in one another, rather than focusing on our differences and the circumstances that drive ...