Bliss is the 20-year-old follow-up to the 2001 film Virgil Bliss, a film about a troubled man Virgil Bliss, played by Clint Jordan (Film Independent Spirit Award Nominee for Virgil Bliss, and TV series’ American Crime Story, This is Us), who just wants to settle down with his wayward girlfriend. In Bliss, that man has settled with a new girl Amy (Faryl Amadeus who plays Amy and Jo). Both are opioid addicts in a relationship that thrives off the addiction. However, their bond is tested when a celebration takes a bad turn. Virgil, going by the name Dwayne, is left questioning if he truly knows the woman he loves.
In the middle of a crisis, lands Jo (Amadeus), Amy’s sister. She is a strait-laced, uptight holy roller who will not leave Virgil alone. Worse than that, she moves right in and rearranges Virgil’s life in a day. The entire time, Sweet, pious Jo refuses to reveal the reason for her trip. Instead, she seems to take joy in watching Virgil build a web of lies about what is actually going on in his and Amy’s home.