The study of genes that contribute to longevity is a developing science.
It is estimated that about 25% of the variation in human lifespan is determined by genetics, but the specific genes and how they contribute to longevity are not well understood
However, some gene variants have been associated with a longer life span. For example, variations in genes such as FOXO3, CETP, APOE, P53, SIRT1, and DAF-16 have been linked to longevity and age-related diseases
These genes are involved in processes such as DNA repair, lipid metabolism, aging, and cell cycle regulation, but while genetics play a role in life expectancy, it’s important to note that lifestyle and environmental factors also significantly influence longevity.