It seems like an obvious question, right? In the post-Van Leeuwenhoek era we can look at whatever part of the body is diseased under a microscope and see, you know, microbes — the usual suspects.
Except when we can’t. And there are plenty of cases where we can’t — where the microbe is too small to be seen without more advanced imaging techniques, like viruses — or when the pathogen is sparsely populated or hard to culture like mycobacterium.
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